2016 Mercedes-Benz E 350: common problems
The maker issued 84 service bulletins for this year. Details by component below, with sources.
Key figures
- Technical service bulletins (TSB)
- 84
Components owners complain about
| Component | Owner complaints | involving a crash | Technical service bulletins (TSB) |
|---|---|---|---|
| Electrical system | 0 | 0 | 22 |
| Exterior lighting | 0 | 0 | 13 |
| Equipment | 0 | 0 | 12 |
| Powertrain | 0 | 0 | 11 |
| Structure | 0 | 0 | 10 |
| Engine | 0 | 0 | 6 |
| Visibility | 0 | 0 | 5 |
| Engine and cooling | 0 | 0 | 4 |
| Seats | 0 | 0 | 2 |
| Service brakes | 0 | 0 | 2 |
| Suspension | 0 | 0 | 2 |
| Electronic stability control | 0 | 0 | 1 |
| Lane departure | 0 | 0 | 1 |
| Tires | 0 | 0 | 1 |
Comparison
What to check before buying
- Electrical system. Scan all modules, test the battery and alternator, inspect connectors near the impact zone.
- Exterior lighting. Headlamps, leveling, sensors and mounts after a frontal hit.
- Powertrain. Shift quality under load, harsh shifts, transmission codes, CV joints.
- Structure. Rails, pillars, panel gaps, signs of pulling or welding.
Manufacturer service bulletins
Bulletin titles as filed with NHTSA.
- Complaint Clanking noise from the area of the speakers in the doors
Cause Under analysis. Remedy To narrow down the cause, first of all remove the door trim. • If the noise continues to occur even with the door trim removed, then continue the diagnosis working towards the speaker and…
- Complaint Repeat workshop visit for vehicle vibration while braking from 60MPH. NOTE
Although the symptom is similar to a tire or wheel vibration, it is usually readily noticeable that it is distinctly different if it happens at all times or only while braking. Cause Although the cause of the vibration…
- Complaint A popup is seen on the HU with the message "data connection temporarily not available"
Potentially affected functionalities in NTG4.5, NTG5 1.Weather 2.Local Search 3.IP Radio 4.Send2Car 5.Speech Detection Service 6.Navigation 7.iHeartRadio 8.Traffic Cams Cause MB Apps is sundowned for all vehicles with…
- Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end)
The noise is heard once in each instance when changing direction of travel. Note: Sound file in attachment Cause If the complaint is eliminated by experimentally loosening the outboard collar nut (by 1 turn), the…
- Dear Mercedes-Benz USA Dealers, The part numbers listed in the chart below should no longer be installed,…
Dear Mercedes-Benz USA Dealers, The part numbers listed in the chart below should no longer be installed, and any existing stock must be returned to your facing PDC. The deadline for all dealer returns is no later than…
- Complaint After successful commissioning of the HERMES control unit (N112/9) with XENTRY Diagnosis DVD…
Complaint After successful commissioning of the HERMES control unit (N112/9) with XENTRY Diagnosis DVD 03/2026, the message "SOS - service not activated" appears on the instrument cluster. In addition, the following…
- Complaint There are several types of complaint about noises or poor windshield wiper wiping performance
A: Wiper blades squeaking, chattering, shuddering B: The windshield is not wiped completely (streaking) C: During the downward movement water is pulled back onto the windshield from the A-pillar (Figure 1) D: After…
- Complaint Potential corrosion on the rear axle carrier Cause Due to market-specific conditions such as…
Complaint Potential corrosion on the rear axle carrier Cause Due to market-specific conditions such as moisture, ingress of dirt and/or environmental influences, corrosion can occur on the rear axle carrier Remedy In…
- In our continuing efforts to assure the proper performance of Mercedes-Benz products and to enhance the…
In our continuing efforts to assure the proper performance of Mercedes-Benz products and to enhance the satisfaction of our customers, Mercedes-Benz USA ("MBUSA") is extending the coverage for the exhaust valve…
- The purpose of this letter is to advise you of additional benefits that Mercedes-Benz is providing to you…
The purpose of this letter is to advise you of additional benefits that Mercedes-Benz is providing to you regarding your vehicle ownership. What’s Included In our continuing efforts to assure the proper performance of…
- Mercedes-Benz USA, LLC will provide an Extended Modification Warranty for each vehicle that has received…
Mercedes-Benz USA, LLC will provide an Extended Modification Warranty for each vehicle that has received the Approved Emission Modification. The Extended Modification Warranty period shall be the greater of: (i) 10…
- To enhance the satisfaction of our customers, avoid further costs of litigation and return focus to its…
To enhance the satisfaction of our customers, avoid further costs of litigation and return focus to its core businesses, Mercedes-Benz USA, LLC (MBUSA) has entered into a settlement regarding claims relating to…
NHTSA lists 84 bulletins for this year; the 12 newest are shown here.
Other years of this model
Questions and answers
What are the most common problems with the 2016 Mercedes-Benz E 350?
There are no owner complaints in the NHTSA data for this year; the data comes from 84 manufacturer service bulletins.
How many service bulletins (TSB) were issued for the 2016 Mercedes-Benz E 350?
NHTSA lists 84 manufacturer service bulletins for this year. A bulletin tells dealers how to diagnose or fix a known issue; it is not a recall.
Should I buy a 2016 Mercedes-Benz E 350 from a US auction?
Owner complaints describe defects, not crash damage. Before bidding, check the components listed above and review the lot photos: VinWind builds a report of visible and hidden damage by VIN.
Other 2016 models
Read also
Sources: public NHTSA data (USA): service bulletins and owner complaints; YouTube: links to videos credited to their authors. Complaints are owner statements not verified by NHTSA, and describe defects rather than crash damage. Data updated 2026-11-04.