AI Damage2010 Mercedes-Benz E 350: common problems
Owners of the 2010 Mercedes-Benz E 350 filed 184 complaints with NHTSA, most often about air bags and fuel/propulsion system. Details by component below, with sources.
Key figures
- Owner complaints
- 184
- involving a crash
- 9
What fails most often
- 1 Air bags 37% of all complaints
- 2 Fuel/propulsion system 10% of all complaints
- 3 Electrical system 9% of all complaints
- 4 Suspension 9% of all complaints
- 5 Engine 8% of all complaints
- 6 Powertrain 8% of all complaints
- 7 Service brakes 8% of all complaints
- 8 Structure 6% of all complaints
- Air bags: 68 complaints (37% of all), 3 of them with a crash reported by the owner.
- Fuel/propulsion system: 18 complaints (10% of all).
- Electrical system: 17 complaints (9% of all), 2 of them with a crash reported by the owner.
- Suspension: 17 complaints (9% of all), 2 of them with a crash reported by the owner.
- Engine: 15 complaints (8% of all), 1 of them with a crash reported by the owner.
Symptoms owners describe
How many of the 184 NHTSA complaints mention each symptom (automatic count from complaint text; one complaint can mention several).
Components owners complain about
| Component | Owner complaints | involving a crash | Technical service bulletins (TSB) |
|---|---|---|---|
| Air bags | 68 | 3 | 0 |
| Fuel/propulsion system | 18 | 0 | 0 |
| Electrical system | 17 | 2 | 0 |
| Suspension | 17 | 2 | 0 |
| Engine | 15 | 1 | 0 |
| Powertrain | 14 | 1 | 0 |
| Service brakes | 14 | 1 | 0 |
| Structure | 11 | 2 | 0 |
| Steering | 8 | 0 | 0 |
| Exterior lighting | 5 | 0 | 0 |
| Seats | 4 | 0 | 0 |
| Vehicle speed control | 4 | 2 | 0 |
| Electronic stability control | 3 | 1 | 0 |
| Tires | 3 | 0 | 0 |
What owners report
Short excerpts of NHTSA complaints in the original wording. These are owner statements not verified by NHTSA; personal data removed.
However, my airbag did not deploy and I hit my chest and knees very hard against the steering wheel and dashboard. Airbag deployment is a basic safety feature during an accident particularly in a luxury vehicle like Mercedes Benz that is known for its safety record.
The air bags failed to deploy. The contact sustained injuries that required medical attention. A police report was filed. The vehicle was destroyed. The vehicle was towed to a lot and the manufacturer diagnosed that the crash was not severe enough for the air bags to deploy.
The car rattles. One day I was driving n the seat I was sitting on blew up for no reason. They replace only the inside parts and never the stitching on the seat so I have a ripped seat for something that was not my fault . This call is def a lemon or should be recalled.
I was pulling into a parking spot at my health club. As I was about to stop, my vehicle suddenly and violently accelerated going into the curb, up a dirt berm and over some very large boulders. I never made it over the berm because the car got lodged onto of a large rock.
Car's response was very good and we liked the car very much. On june 16 I drove the car on freeway for about 23 miles then on the road for another mile with couple of red light stops. Then I turned left into the parking lot and right turn in to the parking spot.
It failed to communicate properly with the power steering system, alongside dashboard warnings for the Electronic Stability Program (ESP) and Antilock Braking System (ABS) now my car is parked and I canât drive it. I had to call a tow truck to take it home.
All of sudden blind spot inoperable , turning signal to Rt. , signal goes LT. OR TURNING SIGNAL TO LT. , SIGNAL GOES To RT.
Car was found to have the rear subframe corrosion for issue. But also the brake lines were corroded very badly. They should be covered under the rear subframe extended warranty replacement. The rear brake lines are an frequent issue and almost always shows up when the subframe begins to rot.
When owners complained
NHTSA complaints by filing year. The peak shows at what age the problems show up most.
Comparison
By complaint count this model year ranks 2,209 of 36,656 model years in the NHTSA data (top 6% most complained about).
On average one model year of the E 350 has 96 complaints (23 years in the data). This year has 184, above average.
What to check before buying
- Air bags. Check the SRS light, stored codes and airbag/curtain status after any impact.
- Fuel/propulsion system. Fuel smell, leaks, rough running, fuel-system codes.
- Electrical system. Scan all modules, test the battery and alternator, inspect connectors near the impact zone.
- Suspension. Wheel alignment, control arms, subframe, even tire wear.
Other years of this model
- E 350 20037 sources
- E 350 200410 sources
- E 350 200515 sources
- E 350 2006400 sources
- E 350 2007350 sources
- E 350 2008173 sources
- E 350 200964 sources
- E 350 2011223 sources
- E 350 2012217 sources
- E 350 2013164 sources
- E 350 2014278 sources
- E 350 201531 sources
- E 350 2016135 sources
- E 350 2017104 sources
- E 350 2020225 sources
- E 350 2021226 sources
- E 350 2022161 sources
- E 350 2023148 sources
- E 350 2024168 sources
- E 350 2025175 sources
- E 350 202683 sources
- E 350 20277 sources
Questions and answers
What are the most common problems with the 2010 Mercedes-Benz E 350?
Owner complaints to NHTSA most often mention: air bags, fuel/propulsion system, electrical system. Total complaints: 184. The most frequent symptoms in complaint texts: rust, corrosion (11%), warning lights, check engine (8%), fuel system, fuel smell (7%).
How many service bulletins (TSB) were issued for the 2010 Mercedes-Benz E 350?
NHTSA lists 0 manufacturer service bulletins for this year. A bulletin tells dealers how to diagnose or fix a known issue; it is not a recall.
Should I buy a 2010 Mercedes-Benz E 350 from a US auction?
Owner complaints describe defects, not crash damage. Before bidding, check the components listed above and review the lot photos: VinWind builds a report of visible and hidden damage by VIN.
Other 2010 models
Read also
Sources: public NHTSA data (USA): service bulletins and owner complaints; YouTube: links to videos credited to their authors. Complaints are owner statements not verified by NHTSA, and describe defects rather than crash damage. Data updated 2026-11-05.